Boehringer, Bridge IPF Deal Collapses On Toxicity Concerns

Termination A Setback To Both Companies

The termination of a major idiopathic pulmonary fibrosis collaboration between Bridge Biotherapeutics and Boehringer Ingelheim is a blow to both companies in an increasingly competitive indication, but the Korean biotech says it's still committed to further development of the autotaxin inhibitor and will work out a future development plan.

Broken deal
Bridge Still Committed To Further Development Of BBT-877 • Source: Shutterstock

Bridge Biotherapeutics, Inc. and Boehringer Ingelheim GmbH have agreed to terminate their collaboration and license agreement reached in July 2019 to develop BBT-877, a small molecule inhibitor of autotaxin, for the treatment of idiopathic pulmonary fibrosis (IPF) and various other fibrotic diseases.

The decision is a setback for both companies as the South Korean biotech will now have to determine the fate of its lead asset, while the big German multinational may...

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