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Mereo Licenses Setrusumab To Ultragenyx For Osteogenesis Imperfecta

 
• By Alexandra Shimmings

Ultragenyx hopes to expand its bone disease franchise in a deal that frees up Mereo to focus on its anti-TIGIT immuno-oncology pipeline asset.    

bone histology
Weakened bones are the hallmark of osteogenesis imperfecta • Source: Shutterstock

Ultragenyx Pharmaceutical Inc. has paid $50m upfront to license Mereo BioPharma Group plc’s rare bone disease therapy, setrusumab, for the treatment of the brittle bone disease osteogenesis imperfecta.

The deal will see Ultragenyx fund development of the fully human anti-sclerostin monoclonal antibody up until approval, and it will take commercial rights in the US and the rest of

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