Tech Transfer Roundup: MD Anderson Tackles Cancer In Alliances With UroGen, Xencor, Obsidian

In tandem with buying the rest of Kleo, Tonix licenses molecular degradation technology from Yale. Neurogene, University of Dundee partner on cell therapies for neurological disorders.

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The increasingly busy University of Texas MD Anderson Cancer Center inked three new alliances with biopharmaceutical companies in the past two months, including its second tie-up in less than a year with Xencor, Inc. All told, the Houston-based organization is researching bladder cancer with UroGen Pharma, Ltd., developing bispecific antibodies with Xencor, and working on novel, engineered tumor-infiltrating lymphocytes (TILs) for solid tumors with Obsidian Therapeutics, Inc.

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Lilly Licenses Sangamo’s Capsid Technology For CNS Gene Therapy

 

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AZ’s Oncology R&D Head On China’s Scientific Promise And True Innovation

 

AstraZeneca remains committed to investing in R&D and alliances in China, where Susan Galbraith, the UK major’s head of oncology R&D, sees innovation eventually reaching parity with the US and Europe.

Sumitomo Offloads Asia Pharma Ops To Marubeni For $480m

 
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The latest in a long line of restructuring measures will see Sumitomo Pharma making a stepped sale of its pharma operations in Asia to major Japanese trading house Marubeni.

Asia Deal Watch: Dr. Reddy’s Gets Regional Rights To Pair Of Bio-Thera Biosimilars

 

Plus deals involving GV20/Mitsubishi Tanabe, Kaken/Alumis, AstraZeneca/Alteogen and deal terminations involving Clover/Gavi Alliance and Rhythm/RareStone.

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Amgen’s Rare Disease Portfolio Grows With Second Approved Uplizna Indication

 
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The US FDA approved anti-CD19 antibody Uplizna, from Amgen’s $27.8bn purchase of Horizon in 2023, for IgG4-related disease – a larger market than its original NMOSD indication.

BeiGene Ends Anti-TIGIT Development In Lung Cancer

 
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BeiGene’s Phase III ociperlimab joins the list of failed TIGIT inhibitors, as candidates from Roche, Merck & Co. and others have failed late-stage studies.

Orphans Cling On To Growth Advantage As Market Share Heads Towards 20%

 

It might be the beginning of the end for the orphan drugs party but there is still sales growth enjoyment to be had for the sector, whose star performers are now looking increasingly like mainstream drugs.