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Padcev Positioned For Urothelial Cancer Expansion

US sBLA Planned Soon

 
• By Ian Haydock

First-in-class ADC set for expanded use on the back of additional data, but analysts see first-line setting as probably the main growth driver.

urothelial cancer
Padcev Moving Ahead In Urothelial Cancer Settings • Source: Shutterstock

Seagen Inc. and partner Astellas Pharma, Inc. have presented additional clinical results for Padcev (enfortumab vedotin) confirming significant improvements in both overall and progression-free survival versus chemotherapy in previously treated urothelial cancer patients, and setting up the first-in-class antibody-drug conjugate (ADC) for further approval progress in this setting.

Primary results from the global, 600-patient Phase III EV-301 trial were presented at the virtual American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU) and published in the New...

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