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AstraZeneca And Sanofi March Ahead With Positive Phase III RSV Data

MELODY Data Music To Companies’ Ears

 
• By Alexandra Shimmings

AstraZeneca and Sanofi have leapt forward in their plans to shake up the RSV market with earlier than expected positive data for their passive immunization product nirsevimab. Rival maternal vaccines in development will cast a shadow, however.    

lung illustration
• Source: Shutterstock

An earlier than expected and positive read-out of a Phase III trial of AstraZeneca PLC and Sanofi’s nirsevimab puts the firms firmly in prime position to shake up the substantial and as yet mostly untapped respiratory syncytial virus (RSV) market.

Top-line data from the MELODY study show that the passive immunotherapy met its primary endpoint of a reduction in the...

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In Brief: PolyPid’s D-PLEX100 Aces Phase III Trial, US Partner, Submission Eyed

 
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NewAmsterdam’s CETP Inhibitor Improves Alzheimer’s Biomarkers

 
• By Mandy Jackson

Data from the BROADWAY trial testing LDL-C reduction in adults with ASCVD showed that obicetrapib improved Alzheimer’s disease biomarkers, including tau and amyloid. Analysts think the data could differentiate obicetrapib against competitors in the cholesterol market.