As Scynexis, Inc. prepares to launch Brexafemme (ibrexafungerp) for vaginal yeast infections in August, the New Jersey firm faces the challenges of a genericized market but also the opportunity of a large patient population eager for new therapeutic options. Given those circumstances, Scynexis CEO Marco Taglietti announced a $475 wholesale acquisition cost (WAC) price for the novel antifungal on 29 June, above the $350-$450 price range he cited upon the product’s US approval on 1 June.
“Setting a WAC price is a complex issue, where you need to listen to the payers, to the doctors and to patients,” Taglietti told Scrip. “In our initial conversations that we started almost two years ago, we had feedback indicating that a price between $350 and $450 was going to be acceptable, but this was based just on a hypothetical description of the [drug] profile
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