Horizon Headed For A Breakout Year As Tepezza Relaunch Exceeds Goals

Thyroid eye disease drug Tepezza is now expected to generate more than $1.55bn in full year sales, despite missing a full quarter of revenue.

Tepezza's relaunch is a commercial success • Source: Alamy

Horizon Therapeutics plc's star drug Tepezza (teprotumumab) is fully back up and running after a manufacturing supply issue kept it off the market in early 2021. Revenue for the thyroid eye disease (TED) drug is now expected to exceed $1.55bn in full year sales, the company reported on 4 August.

Tepezza generated $453.3m in revenue in the second quarter, exceeding expectations, after the drug was returned to the market in April. The US Food and Drug Administration approved new manufacturing for Tepezza in March after the company's initial contract manufacturer was redirected by the US government to prioritize COVID-19 vaccine production. (Also see "With Return Of Tepezza Supply, Horizon Is Ready To Get Back To Business" - Scrip, 31 March, 2021

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