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Data PROpel Lynparza To Potential Prostate Cancer Megablockbuster

Combo Of PARP Inhibitor And J&J's Zytiga Delays Progression In All-Comers

 
• By Kevin Grogan

The Phase III PROpel study has shown that a combination of AstraZeneca's Lynparza and Johnson & Johnson's Zytiga significantly delayed disease progression as a first-line treatment for men with metastatic castration-resistant prostate cancer.

Sodertalje, Sweden - April 27, 2014: Three purple flags with the logo for Atrazeneca flying in the wind on top of the flagpoles against the blue sky.

A positive Phase III trial of Lynparza in prostate cancer patients regardless of genetic mutation could lead to a significant label expansion for AstraZeneca PLC's PARP inhibitor that would have a dramatic impact on sales growth.

High-level results from the PROpel Phase III trial have shown that Lynparza (olaparib) in combination with Johnson & Johnson’s hormonal therapy Zytiga (abiraterone) demonstrated a significant improvement in radiographic...

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