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AstraZeneca's Imfinzi/Tremelimumab Combo Conquers HIMALAYA

Improves Overall Survival In Liver Cancer Patients

 
• By Kevin Grogan

After the combination's success in the non-small cell lung cancer POSEIDON study, AstraZeneca's Imfinzi and tremelimumab could now be on the way to approval as a first-line treatment for hepatocellular carcinoma.

himalaya
Astrazeneca scales the heights in HCC trial • Source: Alamy

A combination of AstraZeneca PLC's PD-L1 inhibitor Imfinzi and its much-maligned investigational CTLA-4 inhibitor tremelimumab has sprung a very pleasant surprise by improving survival rates in liver cancer patients.

The UK major has unveiled topline results from the closely watched HIMALAYA Phase III study which showed that a single,...

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More from Therapy Areas

Veru’s Enobosarm Market Potential Enhanced By New Obesity Data

 
• By Aakash Babu

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GSK, Bharat On Shigella Vaccine Phase II Data Timelines, Malaria Vaccine Price Halving

 
• By Vibha Ravi

GSK tells Scrip about timelines for data expected from two Phase II trials for its Bharat Biotech-partnered shigella vaccine candidate, which puts it ahead of Limmatech/Valneva. Meanwhile, a global-first malaria vaccine, also partnered with Bharat, sees an over 50% price cut

Pfizer’s Hympavzi Poised For Broader Hemophilia Label

 
• By Alaric DeArment

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