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Novartis Hopes For Canakinumab In Lung Cancer Nosedive

Second Phase III Fail In NSCLC

 
• By Kevin Grogan

After deciding to examine canakinumab's potential in lung cancer on the back of the CANTOS cardiovascular trial, Novartis designed a major late-stage program in oncology for the interleukin-1 beta inhibitor. The second of those CANOPY trials has just come crashing down.

Canopy
Novartis canopy program needs patching up • Source: Alamy

The possibility that Novartis AG's canakinumab could offer an option in oncology looks increasingly distant now that the anti-inflammatory agent has failed another late-stage lung cancer study.

The Swiss major unveiled topline results from the CANOPY-1 Phase III study which showed that canakinumab did not meet its...

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