Calithera Drops Development Of Lead Candidate Telaglenastat

Interim Phase II Lung Cancer Data Underwhelming

Calithera’s most advanced oncological asset, telaglenastat, has failed in yet another indication, prompting the company to fall back on candidates in-licensed from Takeda just last month.  

Telaglenastat Was First Glutaminase Inhibitor In Clinic • Source: Alamy

Calithera Biosciences, Inc. has terminated development of its lead asset, telaglenastat, based on interim Phase II study data in lung cancer, forcing the company to re-shift its focus to two recently acquired oncology candidates.

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