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Neurocrine Closer To Ingrezza Label Expansion With Huntington’s Chorea Phase III Win

 
• By Joseph Haas

The neuroscience-focused firm plans a 2022 supplemental NDA for Ingrezza following success in the pivotal KINECT-HD study. The biotech needed an R&D success after recent stumbles.

Brain research
Neurocrine thinks Ingrezza can better the competition in Huntington's chorea

Coming off clinical development setbacks, including a failed effort to expand Ingrezza’s label into pediatric Tourette’s syndrome, Neurocrine Biosciences, Inc.reported positive R&D news to its shareholders on 7 December, as the vesicular monoamine transporter 2 (VMAT2) inhibitor hit the primary endpoint and two secondary endpoints in a Phase III trial in chorea associated with Huntington’s disease.

The San Diego-based firm said it will report full data from the pivotal KINECT-HD trial at a medical meeting in 2022 and that it plans to file a supplemental new...

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