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Four Major Clinical Trial Readouts To Watch Out For In Q2

 
• By Ayisha Sharma

Four prominent drug candidates are expecting topline mid- or late-stage data over the next few months. With the help of Biomedtracker's Q2 Outlook Report, we take a look at the assets that could help validate some of the companies developing them, from oncology to psychiatry.

The Countdown Has Started For Several Companies To Release Important Data • Source: Alamy

Day One Biopharmaceuticals, LLC expects top-line Phase II data for its lead candidate, DAY101, in June. The pan-RAF kinase inhibitor is under investigation in the FIREFLY-1 study for pediatric low-grade glioma (pLGG), the most frequent type of brain tumor in children.

The US biotech first got hold of the asset from Takeda Pharmaceutical Co. Ltd. in 2020 and Phase I data suggest it is both safe and efficacious, with no...

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In a study intended to show similar benefit in western patients, PD-1/VEGF-targeting ivonescimab met a progression-free survival endpoint, but missed on OS.

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Merck & Co./Daiichi Pull Patritumab Deruxtecan BLA On Disappointing OS

 
• By Jessica Merrill

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Senti’s Computer-Logic Inspired Cell Therapy Shows Early Promise

 
• By Andrew McConaghie

The biotech believes its logic-gated cell therapies can get round the need for ‘clean targets’ which limit CAR-Ts and ADCs.

In Brief: Nicox Extends Cash Runway As Kowa Advances NCX 470 In Japan

 
• By Sushmita Panda

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GSK’s Bet On Spero’s Oral cUTI Antibiotic Poised To Pay Off With New Phase III Data

 
• By Joseph Haas

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