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Turning Point ROS1/TRK Inhibitor Repotrectinib Could Stand Out On Durability

 
• By Alaric DeArment

The drug showed a high durability of response in ROS1-positive NSCLC patients, a factor that could give it significant differentiation compared with approved agents.

Turning Point's repotrectinib showed a high level of durability of response • Source: Alamy

Turning Point Therapeutics Inc. has the chance to secure a piece of the market for ROS1-positive non-small cell lung cancer with its ROS1/TRK inhibitor, repotrectinib, after presenting positive Phase I/II data that showed efficacy in line with competitors, but with longer durability.

The company announced topline data by blinded independent central review (BICR) from the TRIDENT-1 trial. The data showed confirmed overall...

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