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Moderna COVID-19 Vaccine Data Bring Multivalent Vs. Monovalent Debate Into Focus

 
• By Alaric DeArment

Phase II/III data for mRNA-1273.211 showed superiority against variants of concern to the original Spikevax, but Moderna’s top competitor has questioned the need for multivalent approaches.

Moderna announced Phase II/III data for its bivalent mRNA-1273.211 vaccine candidate • Source: Alamy

The stiff competition between Moderna, Inc. and Pfizer Inc./BioNTech SE on COVID-19 vaccines will likely continue as Moderna has produced positive results for its bivalent vaccine designed to protect against the original strain of the virus as well as variants of concern, while Pfizer/BioNTech develop their own monovalent, Omicron-specific vaccine candidate.

On 19 April, Moderna announced data from one cohort of its Phase II/III study that tested mRNA-1273.211, a bivalent COVID-19...

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