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Bluebird Could Find US Tailwind For Zynteglo After ICER Report

 
• By Alaric DeArment

The cost-effectiveness watchdog now assumes an upfront $2.1m payment instead of five annual payments. The company switched gears to the US after the TDT gene therapy stumbled in Europe.

ICER released a revised version of its report on bluebird bio's Zynteglo • Source: Shutterstock

The Institute for Clinical and Economic Review (ICER) is pulling back from a recommendation for using five annual payments to cover bluebird bio’s gene therapy Zynteglo (betibeglogene autotemcel, beti-cel) in transfusion-dependent beta-thalassemia (TDT) and assuming a single upfront payments of $2.1m, but is still linking that to an outcomes-based agreement.

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