After two major setbacks in Phase III studies, doubts are growing about Roche’s TIGIT inhibitor candidate tiragolumab’s chances of success - but the company insists the drug can still deliver in non-small-cell lung cancer (NSCLC).
Roche Stays Upbeat Amid Skepticism On Tiragolumab’s Chances
Confirms Trial Weighted Towards Overall Survival Endpoint
Analysts are keen to know more about the statistical weighting of Roche’s SKYSCRAPER 1 study of the TIGIT inhibitor, while Merck & Co can learn from their rival’s slip-up for their own trial design.

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