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Vaccitech’s Immunotherapy Combo With Opdivo Shows Hepatitis B Promise

Searching For A Functional Cure

 
• By Andrew McConaghie

The UK company did not profit greatly from its role in COVID-19 vaccine, Vaxzevria, but hopes the same technology can form part of a breakthrough in hepatitis B.

ILC Congress 2022 London
Numerous new studies aiming for a functional cure in hepatitis B are being presented at the International Liver Congress in London. • Source: EASL

Shares in UK-based Vaccitech climbed by more than 40% after it reported encouraging early results from its ChAdOx1 vaccine platform used in a hepatitis B therapy, which looked strongest when combined with Bristol Myers Squibb’s immuno-oncology product Opdivo.

The news lifted the NASDAQ-listed company’s share price to $5.82 on 23 June, suggesting renewed belief in its next vaccine/immunotherapy...

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