New Era For Schizophrenia Therapy Beckons As Karuna Soars On Promising Phase III Data

Mechanism Exceeds Efficacy Expectations

The PureTech Health-founded entity believes it has made a significant step forward in the treatment of schizophrenia with its muscarinic-receptor acting agent KarXT, which could offer a completely new way to address all three symptom domains of the disease.    

Schizophrenia
• Source: Shutterstock

Karuna Therapeutics, Inc. hopes to raise at least $600m on the back of better-than-expected Phase III efficacy data for its novel therapy for schizophrenia that have set the product on a path to a US regulatory filing mid-next year.

The M1/M4-preferring muscarinic receptor agonist candidate, KarXT (xanomeline-trospium), has achieved positive results in a second Phase III trial, EMERGENT-2, meeting its

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Clinical Trials

More from R&D