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Pharma, Non-Profits Ally To Advance TB Drug Combinations

Goal Is Shorter Duration Treatment Regimens

 
• By Mandy Jackson

The Project to Accelerate New Treatments for Tuberculosis (PAN-TB) is pulling together philanthropic, non-profit and private sector participants to collaboratively run Phase II trials for five drugs from Janssen, Otsuka, the TB Alliance and the Bill & Melinda Gates Medical Research Institute.

3D human lungs medicine microscopic research concept. Therapy of tuberculosis hospital poster template vector illustration
The PAN-TB collaboration will test shorter-term, all-oral regimens • Source: Shutterstock

The Project to Accelerate New Treatments for Tuberculosis (PAN-TB) is taking two TB drug combinations into Phase II clinical trials to see if one or both of the regimens can effectively treat the disease with a shorter duration of therapy, reducing the burden on both patients and health care systems in resource-constrained countries where TB is most prevalent.

PAN-TB, which announced a joint development agreement on 17 August, is a collaboration between the philanthropic, non-profit and private sectors that aims to develop better treatments for all forms of...

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