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ESMO: Ayala In Shadow Of SpringWorks In Rare Cancer Race

Israeli Biotech’s Stock Down Despite Desmoid Tumor Success

 
• By Kevin Grogan

The companies’ respective gamma-secretase inhibitors provided positive data for desmoid tumors at the ESMO congress but SpringWork’s nirogacestat impressed the most.

ringside
Ayala in the desmoid tumor ring • Source: Shutterstock

Ayala Pharmaceuticals, Inc. has heralded data from a Phase II/III trial on its investigational drug, AL102, for desmoid tumors, although investors seem concerned that the Israel-headquartered biotech has much to do to compete with rival SpringWorks Therapeutics Inc.'s nirogacestat.

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