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Ipsen’s Onivyde Hits Bullseye In Pivotal First-Line Pancreatic Cancer Trial

But Observers Waiting To Raise Sales Projections

 
• By Ayisha Sharma

The French firm’s Onivyde has succeeded as part of a combination regimen in chemotherapy-naïve pancreatic cancer patients, setting it up for a label expansion, but some experts are keen to see survival data in full before raising guidance.  

Arrow hitting the bullseye on an archery board
Onivyde Is Set For A Label Expansion For Untreated Pancreatic Cancer • Source: Shutterstock

Ipsen SA’s Onivyde (irinotecan liposome injection) has met the primary endpoint of overall survival (OS) in a Phase III trial in untreated pancreatic cancer patients, sparking filing plans, but potential sales depend on data yet to be released, some observers say.

The Phase III NAPOLI 3 trial set Onivyde plus oxaliplatin (Sanofi’s Eloxatin) and 5 FU/LV against gemcitabine (Eli Lilly and Company’s Gemzar) plus nab-paclitaxel (Bristol Myers Squibb Company’s Abraxane) in

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