Questions About Gantenerumab Failure Remain, But Roche Is Not Yet Finished With Alzheimer’s

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Roche’s global head of neurodegeneration, Rachelle Doody, talks to Scrip about the failure of gantenerumab and its next-generation ‘brain shuttle’ technology for Alzheimer’s disease.

Roche_Basel
Roche's 'brain shuttle' technology is a promising 'next gen' technology, but for now has missed out while Eisai and Biogen head to market • Source: Image archive

Roche received a major knockback with the failure of Alzheimer’s candidate gantenerumab in a Phase III studies earlier this month, ending a more than decade-long effort to develop the antibody for patients with early signs of the disease, but it is far from giving up on the notoriously tricky field.

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