At The Edge Of The Cliff: Five Blockbuster Drugs Set To Lose US Patent Exclusivity In 2023

With the advent of 2023, comes the start of the industry’s next patent cliff, with five products that reached billions in sales at their peak set to lose US patent exclusivity during the year. Scrip takes a look into how the affected big pharma firms are preparing for anticipated market erosion and which generic and biosimilar companies are positioned to benefit the most.

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Big Pharma Is Set To Lose Billions In Sales As Copycat Drugs Approach • Source: Shutterstock

Kicking off the list is AbbVie Inc., which has managed to stave off generic challenge to its immunology product Humira (adalimumab) for some time in the US, but can no longer avoid the biosimilars set to debut in that market this year.

The TNF blocker first won US Food and Drug Administration approval in 2002 for rheumatoid arthritis before expanding to conditions...

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