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Long-Term Data Boost Novartis And Roche SMA Challenge To Biogen’s Spinraza

Rivals’ Revenues Could Overtake Spinraza In 2023

 
• By Andrew McConaghie

New long-term data from Novartis’s Zolgensma and Roche’s Erysdi will help close the gap on Biogen’s market leader Spinraza, but the three therapies look set to develop distinct or even complementary roles as the market matures.

Zolgensma
Novartis's Zolgensma (pictured) and Roche's Evrysdi are gaining ground on Biogen's Spinraza • Source: Shutterstock

Novartis and Roche are slowly closing in on market leader Biogen’s Spinraza in spinal muscular atrophy (SMA) and have both just released new data on the long-term benefits of their treatments.

Biogen established the SMA market six years ago with the launch of Spinraza (nusinersen), but since then the antisense product has been squeezed by competition from the arrival of Novartis’s one-time gene therapy, Zolgensma (onasemnogene abeparvovec) in

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