It was a second clinical trial disappointment in as many months for FibroGen, Inc. as the San Francisco-based firm revealed on 7 June that its CTGF-targeted antibody pamrevlumab missed the primary endpoint in the first of two Phase III studies in Duchenne muscular dystrophy (DMD). The failure was in non-ambulatory DMD patients, but a second Phase III study of the candidate in ambulatory DMD patients is expected to report data during Q3.
FibroGen Misses In First Of Two Pivotal DMD Trials
The biotech’s pamrevlumab fails a Phase III study in non-ambulatory Duchenne muscular dystrophy, but the antibody still has a shot in ambulatory DMD, as well as IPF and pancreatic cancer.
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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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