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BMS’s Mezigdomide Myeloma Data Give Glimpse Of CELMoD Future

Phase I/II Results Published In NEJM

 
• By Alaric DeArment

The trial’s principal investigator said the goal is to establish mezigdomide for use in patients who have failed on Pomalyst. BMS is running a head-to-head trial of both drugs.

BMS published data from its Phase I/II study of mezigdomide in the New England Journal of Medicine • Source: Shutterstock

Published Phase I/II data for Bristol Myers Squibb Company’s mezigdomide bolster the case for the drug’s activity and safety in heavily pretreated multiple myeloma patients, particularly those who have received prior BCMA-directed therapies. The results also hint at where the drug could end up fitting into treatment, with patients who have failed on BMS’s Pomalyst (pomalidomide) being an attractive target population.

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