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Structure Emerges In Obesity Race With Oral GLP-1 Agonist

 
• By Joseph Haas

Early-stage data with Structure’s oral GSBR-1290 shows weight loss of 4.9% at four weeks, which appears to top Lilly’s oral GLP-1 data in a Phase Ia trial.

Weight loss therapy
Structure hopes to enter weight loss arena with an oral GLP-1 agonist • Source: Shutterstock

The increasingly competitive weight-loss therapeutic space was shaken up a bit on 29 September when structure-based drug design firm Structure Therapeutics, Inc. unveiled early data indicating that its oral GLP-1 receptor agonist can yield significant weight loss quickly and with a tolerability profile that should be competitive against injectable agents currently in great demand.

Key Takeaways

  • Structure Therapeutics’ oral GLP-1 receptor agonist shows significant weight loss and good tolerability in a small, early-stage study.

San Francisco-based Structure grossed $161.1m in an initial public offering this past February – at a time of constrained IPO...

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