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ASCO: Simcere Targets Suvemcitug OS Win In Platinum-Resistant Ovarian Cancer

 
• By Dexter Jie Yan

In a late-breaker oral presentation at ASCO on the SCORES study with suvemcitug, Simcere revealed a trend favoring an overall survival advantage in platinum-resistant oral cancer, despite immature data.

ovarian cancer
Platinum-resistant ovarian cancer has a mostly poor prognosis • Source: Shutterstock

Simcere Pharmaceutical Group's novel recombinant anti-VEGF antibody suvemcitug has shown a promising overall survival trend in still immature data in platinum-resistant ovarian cancer presented at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago, which could position it well on this benchmark against other current mainstay same-class therapies.

Key Takeaways

  • Simcere is hopeful that its anti-VEGF antibody suvemcitug in combination with chemotherapy can beat chemotherapy alone for platinum-resistant ovarian cancer.

  • As of data cut-off on 8 December, numerical findings from the 421-patient SCORES study show a median overall survival of 16.07 months for suvemcitug versus 14.88 months for placebo (HR 0.79, p=0.1244)

Back in January, the Nanjing-based drug maker announced the placebo-controlled Phase III SCORES trial with suvemcitug in combination with non-platinum chemotherapy had reached its primary endpoint of progression-free

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