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Apellis To Try Again After EMA Rejects Geographic Atrophy Drug

 
• By Andrew McConaghie

The delayed decision from the CHMP is another rejection for Syfovre but Apellis still hopes the regulator may be convinced in a second review later this year.

Apellis

Apellis has received the bad news it has been expecting for some time as the European Medicines Agency’s expert committee has given a thumbs down to its geographic atrophy treatment Syfovre.

The ruling adds to Apellis’ difficulties with Syfovre (pegcetacoplan) in the US market, where sales of the complement C3 cyclic peptide inhibitor drug are still recovering from a safety scare....

Key Takeaways

  • Still overcoming safety concerns in the US, the EU knockback is another blow to Apellis’ plans.

  • The company believes the ruling could be...

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