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Genmab Upbeat About Advancing Acasunlimab As BioNTech Exits

 
• By Kevin Grogan

Analysts are split on the future for acasunlimab after the German biotech pulled out of co-development but Genmab is all set to kick off a Phase III trial in metastatic non-small-cell lung cancer for the bispecific antibody which acts on 4-1BB, a receptor expressed on activated T cells and natural killer cells.

Jan van de Winkel
Jan van de Winkel • Source: Genmab

Genmab A/S's ability to drive compounds through late-stage trials on its own will be put to the test following the news that BioNTech SE has pulled out of a pact to further co-develop acasunlimab for lung cancer.

The Danish biotech is assuming sole responsibility to advance acasunlimab, a PD-L1 x 4-1BB bispecific antibody, after its Germany-headquartered partner...

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Deal Snapshot: Bayer will take over development of the asset once Kumquat completes a Phase Ia clinical trial, but the biotech firm may opt in to share US profits and losses.

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Genmab/AbbVie’s Epkinly Likely To See Label Expansion After Phase III Win

 
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Genmab/AbbVie’s Epkinly Likely To See Label Expansion After Phase III Win

 
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• By Sushmita Panda

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Jazz’s Modeyso Approved For Rare Glioma With Expansion Targeted

 
• By Jessica Merrill

The accelerated approval came three months after Jazz completed the acquisition of Modeyso’s developer, Chimerix.