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Halda Raises $126m For First Clinical Trial Of Its RIPTAC Modality

Heterobifunctional Molecules From A PROTAC Pioneer

 
• By Mandy Jackson

Halda will take its first RIPTAC molecule into a clinical trial in prostate cancer, offering a new small molecule modality in an indication where patients and doctors prefer oral drugs.

Venture capital. Long term business investment
Halda has raised $202m to date • Source: Shutterstock

Induced proximity biology – bringing two molecules together to cause some kind of reaction – is in its heyday via the field of targeted protein degradation with proteolysis targeting chimera (PROTAC) therapeutics reaching previously undruggable targets. Now, Halda Therapeutics, with $126m in new venture capital financing, will conduct its first clinical trial of a novel induced proximity modality from a PROTAC pioneer.

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