Acelyrin Belatedly Drops Izokibep In Its Lead Indications

The group has stopped further development of the IL-17A inhibitor in hidradenitis suppurativa and psoriatic arthritis, and intends to pivot to a thyroid eye disease therapy.  

Acelyrin HQ
• Source: Acelyrin

Acelyrin, Inc. has taken its time in coming to a sensible decision on izokibep. The company has terminated development of its IL-17A inhibitor izokibep in both hidradenitis suppurativa (HS) and psoriatic arthritis (PsA) after a Phase III trial in the former condition yielded positive but unremarkable data.

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