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RemeGen’s China Clinical Win In gMG Paves Way For Global Phase III

 
• By Dexter Jie Yan

Being the Chinese biotech’s backbone asset in the autoimmune disease area, telitacicept, a BlyS/APRIL dual targeting fusion protein, has hit its target in a China-only Phase III study in generalized myasthenia gravis. The candidate is also being investigated in global Phase III trials in systemic lupus erythematosus and Sjögren's syndrome.

Concept of Myasthenia Gravis written on sticky notes isolated on Wooden Table.
Telitacicept's domestic clinical win expected to accelerate global Phase III program for gMG • Source: Shutterstock

RemeGen Ltd. has clinched a major Phase III clinical win for its BlyS/APRIL dual targeting fusion protein telitacicept, the Chinese firm’s backbone asset in the autoimmune disease area, in Chinese patients with generalized myasthenia gravis (gMG).

While numerical details were undisclosed, the positive outcome is expected to accelerate a planned global Phase III program with the drug in the rare disorder, which causes skeletal muscle weakness

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