AstraZeneca PLC’s PI3Kα inhibitor Truqap (capivasertib) won US Food and Drug Administration approval late last year and has quickly become the standard of care in certain patients with breast cancer, but could soon face a challenger in the form of Relay Therapeutics, Inc.’s RLY-2608, which has shown strong results in a Phase I clinical trial.
Relay To Take On AstraZeneca With RLY-2608 In PI3Kα-Mutated Breast Cancer
The firm is planning a head-to-head trial against AstraZeneca’s Truqap after RLY-2608 showed better safety and efficacy in a Phase I trial, including a four-month PFS benefit.
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