Incyte Corporation is going to have a second go at getting its PD1 inhibitor Zynyz (retifanlimab) approved as the first anti PD-1/PD-L1 inhibitor for squamous cell anal carcinoma (SCAC) following a hit in the Phase III POD1UM-303/InterAACT 2 trial presented at the European Society for Medical Oncology meeting in Barcelona, Spain, on 14 September.
ESMO 24: Incyte’s Zynyz Finally Mounts The POD1UM
Persistence has paid off for Incyte’s Zynyz in anal cancer with a Phase III win that should make up for a previous disappointment at the FDA and give a boost to the firm’s pipeline prospects for a post-Jakafi era.
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