Editas Looks To Upregulate Its Fortunes With In Vivo Editing

After ditching its clinical-stage ex vivo candidate in December, the CRISPR-based company is starting all over again with a focus on in vivo therapies and upregulating beneficial genes.

Editas
Editas's first in vivo gene therapy results underwhelmed last year, but the company could build on its leading position in 2022. • Source: Alamy

Editas Medicine is hoping for a reversal of fortunes, having recently abandoned its lead candidate and laid off three quarters of its workforce after failing to find a partner for the asset, reni-cell, an ex vivo sickle cell disease and beta thalassemia gene editing therapy.

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