Roche has sought to temper the long-expected news that its cancer immunotherapy, tiragolumab, has failed in a key Phase III study by announcing a $1.5bn buyout of the cell therapy company Poseida.
Roche Softens TIGIT Blow With Poseida Buyout
The SKYSCRAPER-01 trial’s failure to generate an overall survival benefit is the biggest blow yet to the TIGIT inhibitor class, but Roche looking to move on with its buyout of the CAR-T therapy company.

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Merck & Co., which already has an oral PCSK9 inhibitor in Phase III, licensed Hengrui’s Lipoprotein(a)-lowering small molecule HRS-5346 outside of Greater China for $200m up front.
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