Regeneron’s Eylea Faces Pressure, But Pipeline Shows Strength

The drug maker’s top-selling Eylea franchise faces market challenges as biosimilars roll out, but Regeneron is confident about a pipeline that includes multiple significant catalysts in 2025.

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Regeneron Pharmaceuticals expects to see downward pressure on the 2mg version of Eylea (aflibercept) continue after 2024, but demand for the VEGF inhibitor has remained high despite the introduction of the first aflibercept biosimilar.

The Tarrytown, NY-based drug maker announced its fourth-quarter and full-year 2024 earnings on 4 February, reporting that quarterly revenues increased by 10% to $3

Key Takeaways
  • Regeneron reported that its fourth-quarter sales grew 10% to $3.79bn, while full-year sales for 2024 grew 8% to $14.2bn.
  • Libtayo, the company’s PD-1 checkpoint inhibitor, crossed the blockbuster threshold, with full year 2024 sales of $1.22bn

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