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Inventiva Tries Restructuring To Reach Phase III Finish Line In MASH

 
• By Joseph Haas

Large headcount reduction and ending preclinical programs may give Inventiva runway to report Phase III data for lanifibranor that are expected during the second half of 2026.

Inventiva is cutting headcount and ending preclinical R&D to conserve cash (Shutterstock)

After overcoming a financial shortfall in 2024, Inventiva is cutting staff by 50% and ceasing its preclinical research and development efforts to try to make its money last long enough to get Phase III data for its metabolic dysfunction-associated steatohepatitis (MASH) candidate lanifibranor, expected during the second half of 2026.

Key Takeaways
  • With current runway only into Q3 of this year, Inventiva announced a 50% staff cut to get it to the finish line for Phase III data in MASH.

Once viewed as potentially second in line to reach the market with a MASH drug, Inventiva has fallen off that...

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