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Cidara’s Fortunes Improve Quickly With Non-Vaccine Flu-Prevention Data

 
• By Joseph Haas

Having recently abandoned the antifungal space, Cidara’s stock soared on Phase IIb data showing that its drug-Fc conjugate prevents seasonal flu at rates from 57%-76%.

Influenza
Cidara's Phase IIb flu prevention data tops prophylactic effect typically seen with vaccines • Source: Shutterstock

Cidara Therapeutics’ business outlook improved substantially on June 23 after releasing pre-market Phase IIb data for its non-vaccine seasonal influenza prevention agent showing better prophylaxis capabilities than usually seen with flu shots. The San Diego firm said on a same-day call that it hopes to convene end-of-Phase II talks with the US Food and Drug Administration soon to plan a pivotal study.

Key Takeaways
  • Cidara unveiled Phase IIb data for its non-vaccine flu prevention agent CD388 showing statistical significance for preventive efficacy at three tested doses.

The positive topline Phase IIb data for CD388, a drug-Fc conjugate (DFC), provide validation for Cidara’s change of course in...

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