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Vir Scores In Oncology Pivot With Strong Early T-Cell Engager Results

 
• By Alaric DeArment

Five months after taking over the dual-masked T-cell engagers from Sanofi amid a restructuring, the company posted promising initial Phase I data from its PSMA- and HER2-targeting IO candidates.

• Source: Shutterstock

Vir Biotechnology’s move from focusing solely on antiviral drugs to incorporating oncology into its pipeline has shown early signs of potentially paying off as the company announced safety and efficacy data for two T-cell engager (TCE) antibodies, VIR-5818 and VIR-5500, which it licensed from Sanofi in August.

The San Francisco-based biotech announced 8 January what it called encouraging safety and efficacy data from dose-escalation trials of VIR-5818,...

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