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Novo Nordisk’s CagriSema Hits Mark, But Misses Target In Obesity

 
• By Alaric DeArment

Efficacy for the drug came in below investors’ expectations for beating Lilly’s Zepbound, while analysts said a lower percentage of people remaining on the highest dose suggested tolerability issues.

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The stakes had been high for Novo Nordisk’s Phase III REDEFINE 1 clinical trial of its next-generation obesity agent CagriSema (cagrilintide 2.4mg and semaglutide 2.4mg), which has been Novo’s best hope to extend its leadership position in the fast-growing obesity market. While the topline REDEFINE 1 results were not a losing hand, they were not a full house either.

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