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Gilead/Merck’s Lenacapavir/Islatravir Combination Could Help With HIV Stigma

 
• By Alaric DeArment

Gilead presented 48-week data for the combination of weekly oral lenacapavir/islatravir, showing results consistent with 24-week data. A Phase III program will soon begin.

Gilead

The latest data from the Phase II study of the weekly oral combination of Gilead Sciences Inc.’s lenacapavir and Merck & Co., Inc.’s islatravir in patients living with HIV shows that efficacy is holding up compared with earlier data presented seven months ago, and now the combination is about to head into Phase III. But it will especially make a difference for patients who have difficulty in a psychological sense with having to take a pill to manage their disease every day.

Key Takeaways
  • Data at IDWeek from the Phase II study of the weekly oral combination of Gilead’s lenacapavir and Merck’s islatravir showed that 24-week safety and efficacy numbers presented in March have held up at 48 weeks.

Gilead presented 48-week data from the Phase II study in a late-breaking abstract at IDWeek on 19 October, an update...

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