Bristol-Myer Squibb's deal to pay up to $2 billion for ImClone System's cancer drug, IMC-C225, should be viewed as a broad strategic move more than a product license. BMS badly needs to shore up its cancer franchise following the expiration of its Taxol patent. It paid dearly for IMC-C225, but unlike some competitors, BMS had no epidermal growth factor receptor-based drug in its pipeline. And because EGFr drugs are widely expected to achieve blockbuster status and be used in combination therapies, BMS needed one as a foundation asset around which to sell its other cancer drugs.
The loss of patent protection last year on paclitaxel (Taxol) has posed the biggest threat to Bristol-Myers Squibb Co. 's leadership position in oncology drugs in over a decade. Never a company reliant on internal R&D, it badly needed to in-license a major late-stage or already-marketed product to sustain its franchise.
Bristol's whopping September deal for ImClone Systems Inc. 's lead cancer product, IMC-C225, should therefore be viewed more as...
Despite limited evidence of commercial impact, pharmaceutical companies are making massive strategic investments in AI biologics platforms. The question isn't whether the technology shows promise; it's whether that promise can translate to measurable business results.
Against a backdrop of shifting trade policies, the end of multilateral market approaches and renewed focus on supply chain resilience, medtechs are doubling down on innovation in products and processes – using AI – and keeping unmet needs and outcomes in the center of the target.
While biopharma companies experiment with genAI, agentic AI is rapidly shifting the work paradigm towards one of autonomous digital workers that can handle entire process flows.
Biotech companies are pursuing diverse AI strategies beyond expensive custom data generation: foundation model fine-tuning, data-efficient computational methods and targeted proprietary datasets. In Vivo takes a look at some examples.
In Vivo sits down with Ying Tam, CSO at Acuitas Therapeutics, to discuss the company's role in delivering the first personalized CRISPR treatment to an infant and the clinical implications of new lipid nanoparticle technologies.
When it came to AI-related deals, the second quarter of 2025 was characterized by mostly modest financings.
The big pharma CEO with the highest-valued compensation in 2024 was David Ricks of Eli Lilly, while Pfizer and J&J executives slipped into third and fourth place behind AbbVie's now retired chief Richard Gonzalez. European firms brought up the rear.
