1. In Vivo
  2. >>Innovation

Two Cheers for Evidence-Based Medicine

In recent years, evidence-based medicine has had an important influence on cardiovascular devices, but it's easy to overlook the staying power of subjective judgment. At a session on "What's the Science on Niche Devices?" held during this year's American Heart Association meeting, the cardiologist-audience clearly didn't seem deterred from using certain devices such as DCA and rotoblators, despite equivical or mediocre results in clinical trials.

At this year's American Heart Association (AHA) meeting, the title of the Sunday morning clinical session on interventional cardiology, "What's the Science on Niche Devices?," precisely captured the growing influence of evidence-based medicine in cardiology today. Assessing the value of four different interventional devices—devices used in direct coronary atherectomy (DCA), rotoblators, cutting balloons, and the AngioJet anti-thrombus device—cardiologists reviewed the relevant clinical trials to determine when each device has proven effective and when it hasn't.

The data on the AngioJet device, manufactured by Possis Medical Inc. , and the cutting balloon, developed by Interventional Technologies Inc. (IVT), now part of Boston Scientific Corp....

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on In Vivo for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required
Start Free Trial

Already a subscriber?

More from Innovation

Leaders At The Frontier: Conversations From SynBioBeta 2025

 
• By David Wild

Mini-profiles of five synthetic biology companies and their leaders from SynBioBeta 2025 reveal how AI integration, data-driven platforms and interdisciplinary teams are revolutionizing drug discovery and manufacturing.

From IVF Failure To Fertility Breakthroughs: Freya’s Microbiome Mission

 
• By Jo Shorthouse

Named after the Norse goddess of fertility, Freya Biosciences is mapping the reproductive microbiome with a host of women's health indications as the final destination.

ML-Assisted Genetic Risk Score Predicts GLP-1 Adverse Events

 
• By David Wild

Phenomix Science presented new data at Digestive Disease Week 2025 showing its machine learning-assisted genetic risk score can predict nausea and side effects from GLP-1 receptor agonists, aiding personalized obesity treatment.

The pre|CISION Approach: How Avacta Is Making Toxic Cancer Drugs Safe And More Effective

 
• By Jo Shorthouse

Avacta's approach to drug delivery is showing how 'masked' chemotherapy can dramatically improve safety profiles while maintaining or enhancing efficacy where it matters most.

More from In Vivo

US Health System Redesign Critical, NAM’s Medical Experts Warn Trump Government

 
• By Ashley Yeo

The whirlwind back-and-forth on US tariffs and Robert F. Kennedy jr.’s plans to deregulate health care have become all-preoccupying, but the National Academy of Medicine was first to set out President Trump’s health administration priorities.

Podcast: “Powerful Yet Unexplored”: Commit Biologics Tackles The Complement System

 
• By Anabel Costa-Ferreira

Mikkel Wandahl Pederson, CEO and chief scientific officer at Commit Biologics, discussed the company’s mission to harness the powerful complement system for the treatment of serious diseases.

ML-Assisted Genetic Risk Score Predicts GLP-1 Adverse Events

 
• By David Wild

Phenomix Science presented new data at Digestive Disease Week 2025 showing its machine learning-assisted genetic risk score can predict nausea and side effects from GLP-1 receptor agonists, aiding personalized obesity treatment.