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JCR Pharma: Crossing Oceans And The Blood-Brain Barrier

 
• By Ben Comer

After 45 years as a domestic Japanese biopharmaceutical company, JCR Pharmaceuticals is expanding into global markets. The company is betting that its manufacturing strength – which helped land a COVID-19 vaccine manufacturing deal with AstraZeneca – and blood-brain barrier crossing J-Brain Cargo technology will lead to success in Western markets.   

Japanese abstract waves

JCR Pharmaceuticals Co., Ltd., headquartered in Ashiya, Hyōgo Prefecture, holds claim to several “firsts” in Japan. In 2010, the company launched Japan’s first biosimilar product (Epoetin alfa BS injection), in partnership with Kissei Pharmaceutical Co. In 2015, the company commercialized the first allogeneic stem cell therapy in Japan (Temcell, licensed fromMesoblast Limited). And on 23 March 2021, JCR received approval in Japan for Izcargo (pabinafusp alfa 10 mL, intravenous drip infusion), the first enzyme replacement therapy capable of crossing the blood-brain barrier. (Also see "Latest Japan Approvals Include World-First For Pabinafusp" - Pink Sheet, 25 March, 2021.)

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