1. In Vivo

Seres And Ferring Go Head-To-Head In Recurrent C. Difficile Market

Two New Microbiome Medicines Launched In 2023

 
• By David Wild

After the historic approvals of Seres’ and Ferring’s microbiome-based treatments for recurrent Clostridioides difficile infection, the two companies are waiting to see who dominates the $1bn market. Physicians say patients will steer the choice of treatments.

Patients with recurrent C. difficile now have two comparable treatments • Source: Shutterstock

For patients in the US with recurrent Clostridioides difficile infection (rCDI), the recent approval of two safe and effective treatments is a win. Now the question for Seres Therapeutics, Inc. and Ferring Pharmaceuticals is whether either will be able to dominate the market.

Rebyota (fecal microbiota, live – jslm) was approved by the US Food and Drug Administration in November 2022 and Vowst (fecal microbiota spores, live-brpk) received the regulator's nod just a few months later, in April 2023. Both are indicated for the prevention of rCDI in adults after antibiotic treatment for an initial recurrence

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