EuroPCR In Brief
MitraClip: Abbott's transcatheter mitral valve repair device kept well within the non-inferiority margin compared to surgery on the composite endpoint of freedom from death, from follow-up mitral valve surgery and from greater-than-mild mitral regurgitation after two years of follow-up, EVEREST II trial investigator Ted Feldman, M.D., NorthShore University Health System, reported May 25 at the EuroPCR conference in Paris. And in a one-year subgroup analysis, there was no statistical difference in safety and similar efficacy outcome in MitraClip patients with either functional or degenerative mitral regurgitation, he said. MitraClip attracted significant attention in March when Feldman reported it has met its one-year non-inferiority efficacy endpoint and 30-day superiority safety endpoint versus open surgery at the American College of Cardiology annual meeting (1"The Gray Sheet" March 22, 2010). The EuroPCR MR subgroup analysis is particularly important, said Michael Weinstein, a J.P. Morgan analyst, because it "suggests that Abbott will be able to target the entire [MR] market, significantly increasing the potential opportunity.
More from Archive
Editor’s note: This is your final call to participate in the survey to better understand our subscribers’ content and delivery needs. The deadline is 20 September.
Editor’s note: We are conducting a survey to better understand our subscribers’ content and delivery needs. If there are any changes you’d like to see in coverage topics, content format or the method in which you receive and access Medtech Insight, or if you love it how it is, now is the time to have your voice heard.
Medtronic announced it received expanded MRI labeling for its DBS systems, which is critical, given that almost 70% of all DBS-eligible patients will likely need an MRI at some point in their care, says Ashwini Sharan, CMO for Medtronic Neuromodulation.
In this episode, Medtech Insight reporter Natasha Barrow speaks to LungLife AI CEO Paul Pagano. Lung Life AI is a US-based AIM-listed medical technology company that has developed a liquid biopsy test for the early detection of lung cancer called Lung LB. Pagano runs through the highlights of Lung Life AI journey to date and its future ambition for a strategic partnership. He also provides advice to similar diagnostic companies seeking reimbursement andcompliance with the US FDA Lab Developed Test ruling.
More from Medtech Insight
An interactive look at recent executive-level company changes and promotions in the medical device and diagnostics industries.
Q’Apel Medical has pulled its aspiration system for stroke thrombectomy from the market after concerns raised by the US FDA in a February warning letter.
The FDA's final LDT ruling was struck down in federal court last month. For now, diagnostic companies can commercialize under CLIA regulations or apply for FDA approval. McDermott and Tribun Health have shared insights on the risks, pros and cons of both regulatory routes.