Start-Up Spotlight: 4C Addresses Mitral Regurgitation With Unique 'Dome' Device

29 Jun 2017

US firm 4C Medical Technologies is developing a unique solution to mitral regurgitation that sits outside the valve and takes advantage of the native valve's remaining function while preventing mitral regurgitation. The Minnesota-based start-up is currently funded by angel investors and "friends and family," but expects to raise a $15m Series B round in early 2018.

MT1706_4C-Mitral-Valve-Device_790 — 4C Mitral Valve Device • Source: 4C Medical Technologies

4C Medical Technologies is addressing the unique problems of dysfunctional mitral valves with a device that sits in the atrium rather than within the valve annulus itself, which will hopefully allow it to last longer and avoid many of the complications faced by other minimally invasive mitral valve replacement technologies.

The mitral valve is more challenging to address than the aortic valve currently addressed by a variety of transcatheter devices...